Accession | GenProp0946 |
Name | GDP-L-colitose biosynthesis |
Type | METAPATH |
Description | GDP-L-colitose, a 3,6-dideoxy hexose sugar is formed from GDP-4-ket-6-deoxymannose in a two-step reaction carried out by the ColC and ColD gene products. Colitose is a component of the O111 and O55 E. coli O-antigens. |
JCVI Role | Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
Literature References | [ 1 ]Alam J, Beyer N, Liu HW Biosynthesis of colitose: expression, purification, and mechanistic characterization of GDP-4-keto-6-deoxy-D-mannose-3-dehydrase (ColD) and GDP-L-colitose synthase (ColC). Biochemistry. 2004 Dec 28;43(51):16450-60. PMID 15610039 |
|