Genome Property Definition Page

Accession

GenProp1010

Name

accessory Sec system, Actinobacterial type

Type

SYSTEM

Description

The gene symbol secA2 arose twice in the literature for accessory secretory systems acting in addition to the SecA (pre)protein translocase system. This genome property describes the form as it occurs in Mycobacterium tuberculosis and M. smegmatis. The two SecA2 families are both related to SecA but probably are not orthologous to each other.

Literature References

[ 1 ]Braunstein M, Brown AM, Kurtz S, Jacobs WR Jr Two nonredundant SecA homologues function in mycobacteria. J Bacteriol. 2001 Dec;183(24):6979-90. PMID 11717254
[ 2 ]Gibbons HS, Wolschendorf F, Abshire M, Niederweis M, Braunstein M Identification of two Mycobacterium smegmatis lipoproteins exported by a SecA2-dependent pathway. J Bacteriol. 2007 Jul;189(14):5090-100. Epub 2007 May 11. PMID 17496088

Components

Step Name	Step Num	Required	Evidence (Method)	Evidence Go Terms
accessory Sec system translocase SecA2	SecA2	YES	TIGR04221 (HMM): accessory Sec system translocase SecA2