Genome Property Definition Page

AccessionGenProp1051
NameO10(Ec) antigen biosynthesis
TypeMETAPATH
DescriptionThe E. coli O10 antigen is a branched pentasaccharide with the structure [->3)aLRha{(2<-1)aDFuc4NAcyl}(1->3)aLRha(1->3)aDGal(1->3)bDGlcNAc(1->], where the acyl group is heterogeneous and composed of 60% acetyl and 40% D-3-hydroxybutyryl. The composition of the O10(Ec) cluster has not been previously reported and was sequenced at JCVI as project ostec03.
JCVI RoleBiosynthesis and degradation of surface polysaccharides and lipopolysaccharides

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
O10(Ec)-associated putative D-Fuc4N acyltransferaseAcTRYES2968 (RULE_BASE)
O10(Ec)-associated putative D-Fuc4N acyltransferaseAcTRYES2968 (RULE_BASE)
O10(Ec)-associated putative D-Fuc4N acyltransferaseAcTRYES2968 (RULE_BASE)
source of dTDP-4-acetamido-4,6-dideoxy-D-galactose (dTDP-Fuc4NAc)Fuc4NAcYESGenProp0972 (GENPROP): dTDP-4-acetamido-4,6-dideoxy-D-galactose (dTDP-Fuc4NAc) biosynthesis
source of dTDP-4-acetamido-4,6-dideoxy-D-galactose (dTDP-Fuc4NAc)Fuc4NAcYESGenProp0972 (GENPROP): dTDP-4-acetamido-4,6-dideoxy-D-galactose (dTDP-Fuc4NAc) biosynthesis
source of dTDP-4-acetamido-4,6-dideoxy-D-galactose (dTDP-Fuc4NAc)Fuc4NAcYESGenProp0972 (GENPROP): dTDP-4-acetamido-4,6-dideoxy-D-galactose (dTDP-Fuc4NAc) biosynthesis
O10(Ec)-associated L-rhamnose alpha-1,2-(4-N-acyl)-D-fucosaminyltransferaseGT-1YES2964 (RULE_BASE)
O10(Ec)-associated L-rhamnose alpha-1,2-(4-N-acyl)-D-fucosaminyltransferaseGT-1YES2964 (RULE_BASE)
O10(Ec)-associated L-rhamnose alpha-1,2-(4-N-acyl)-D-fucosaminyltransferaseGT-1YES2964 (RULE_BASE)
O10(Ec)-associated L-rhamnose alpha-1,3-L-rhamnosyltransferaseGT-2YESTIGR01556 (HMM-CLUST): rhamnosyltransferase
O10(Ec)-associated L-rhamnose alpha-1,3-L-rhamnosyltransferaseGT-2YESTIGR01556 (HMM-CLUST): rhamnosyltransferase
O10(Ec)-associated L-rhamnose alpha-1,3-L-rhamnosyltransferaseGT-2YESTIGR01556 (HMM-CLUST): rhamnosyltransferase
O10(Ec)-associated D-galactose alpha-1,3-L-rhamnosyltransferaseGT-3YES2966 (RULE_BASE)
O10(Ec)-associated D-galactose alpha-1,3-L-rhamnosyltransferaseGT-3YES2966 (RULE_BASE)
O10(Ec)-associated D-galactose alpha-1,3-L-rhamnosyltransferaseGT-3YES2966 (RULE_BASE)
O10(Ec)-associated N-acetyl-D-glucosamine alpha-1,3-D-galactosyltransferaseGT-4YES2967 (RULE_BASE)
O10(Ec)-associated N-acetyl-D-glucosamine alpha-1,3-D-galactosyltransferaseGT-4YES2967 (RULE_BASE)
O10(Ec)-associated N-acetyl-D-glucosamine alpha-1,3-D-galactosyltransferaseGT-4YES2967 (RULE_BASE)
source of L-rhamnoseRhaYESGenProp0183 (GENPROP): dTDP-L-rhamnose biosynthesis from dTDP-4-dehydro-L-rhamnose
source of L-rhamnoseRhaYESGenProp0183 (GENPROP): dTDP-L-rhamnose biosynthesis from dTDP-4-dehydro-L-rhamnose
source of L-rhamnoseRhaYESGenProp0183 (GENPROP): dTDP-L-rhamnose biosynthesis from dTDP-4-dehydro-L-rhamnose
O10(Ec)-antigen transporter (flippase) wzxwzx10YES2963 (RULE_BASE)
O10(Ec)-antigen transporter (flippase) wzxwzx10YES2963 (RULE_BASE)
O10(Ec)-antigen transporter (flippase) wzxwzx10YES2963 (RULE_BASE)
O10(Ec)-antigen polymerase wzywzy10YES2965 (RULE_BASE)
O10(Ec)-antigen polymerase wzywzy10YES2965 (RULE_BASE)
O10(Ec)-antigen polymerase wzywzy10YES2965 (RULE_BASE)