Genome Property Definition Page
Accession | GenProp1074 | |
Name | type V secretion | |
Type | SYSTEM | |
Description | Type V secretion systems (T5SS) are most commonly the classical monomeric autotransporters (type Va), in which a C-terminal outer membrane (OM) beta barrel domain functions as a translocator through the OM for an N-terminal passenger domain of the same polypeptide chain. Many type Va autotransporters cleave autocatalytically to release the passenger domain. In type Vb systems, called two-partner secretion systems, the passenger and translocator domains are in separate polypeptides. Additional variant forms Vc, Vd, and Ve have also been described. A special type of signal peptide (PF13018) tethers the nascent polypeptide chain to the Sec apparatus in some autotransporters to allow proper completion of C-terminal domain folding in the OM. | |
JCVI Role | Protein and peptide secretion and trafficking | |
Parent Property | GenProp0179: protein transport | |
Literature References |
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Gene Ontology Term | GO:0046819: protein secretion by the type V secretion system (biological_process) |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
type V secretion system signal peptide | T5SSsig | NO | PF13018 (HMM): type V secretion system signal peptide | GO:0046819: protein secretion by the type V secretion system |
T5SS outer membrane translocator | autotran | YES | TIGR01414 (HMM): outer membrane autotransporter barrel domain PF03865 (HMM): hemolysin secretion/activation protein, ShlB/FhaC/HecB family | GO:0046819: protein secretion by the type V secretion system GO:0046819: protein secretion by the type V secretion system |
Parent Properties
Accession | Name |
---|---|
GenProp0179 | protein transport |
Sibling Properties
Accession | Name |
---|---|
GenProp0052 | type III secretion |
GenProp0053 | type II secretion |
GenProp0054 | type IV secretion |
GenProp0059 | type I secretion |
GenProp0127 | Tat (Sec-independent) protein export |
GenProp0205 | signal recognition system, bacterial |
GenProp0207 | lipoprotein localization system lolABCDE |
GenProp0209 | Sec system preprotein translocase |
GenProp0295 | prokaryotic N-terminal cleavage/methylation, type IV pilin-like |
GenProp0326 | protein sorting system, PEP-CTERM/exosortase (generic) |
GenProp0626 | protein sorting system, sortase type, LPXTG/SrtA class |
GenProp0664 | protein sorting system, sortase type, SrtB class |
GenProp0669 | protein sorting system, putative, exosortase G class |
GenProp0735 | type VI secretion |
GenProp0778 | protein sorting system, GlyGly-CTERM/rhombosortase |
GenProp0844 | accessory Sec system for serine-rich glycoprotein transport |
GenProp0845 | protein sorting system, KxYKxGKxW class |
GenProp0847 | exosporium |
GenProp0859 | protein sorting system, proteobacterial dedicated sortase type |
GenProp0904 | type VII secretion, Actinobacteria form |
GenProp0905 | type VII secretion, Firmicutes form |
GenProp0928 | OMP chaperone system: SurA-Skp-DegP |
GenProp0957 | protein sorting system, SipW class |
GenProp0978 | protein sorting system, PGF-CTERM/archaeosortase A |
GenProp0979 | protein sorting system, PEF-CTERM/archaeosortase C |
GenProp0980 | protein sorting system, putative, exosortase F class |
GenProp0983 | protein sorting system, VPXXXP-CTERM/archaeosortase B |
GenProp0985 | protein sorting system, VPDSG-CTERM/exosortase C |
GenProp0986 | protein sorting system, VPLPA-CTERM/exosortase D |
GenProp0987 | protein sorting system, cyano-PEP-CTERM class |
GenProp0989 | protein sorting system, VPEID-CTERM/exosortase E |
GenProp0993 | protein sorting system, PIP-CTERM/archaeosortase D |
GenProp0996 | protein sorting system, IPTLxxWG-CTERM/exosortase H |
GenProp0999 | Por secretion system |
GenProp1005 | protein sorting system, putative, exosortase J class |
GenProp1054 | protein sorting system, MSEP-CTERM/exosortase K |
GenProp1055 | protein sorting system, PEFG-CTERM/thaumarchaeosortase |
GenProp1087 | protein sorting system, vault protein/exosortase N |
GenProp1102 | protein sorting system, CGP-CTERM/unknown of Thermococcaceae |
GenProp1103 | protein sorting system, Synergist-CTERM/unknown of Synergistetes |