|Domain Trusted Cutoff||293.40|
|Domain Noise Cutoff||146.10|
|Mainrole Category||Energy metabolism|
|Gene Ontology Term||GO:0005737: cytoplasm cellular_component|
| ||GO:0006083: acetate metabolic process biological_process|
| ||GO:0006113: fermentation biological_process|
| ||GO:0008776: acetate kinase activity molecular_function|
|Entry Date||Apr 20 1999 2:06PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||Acetate kinase is involved in the activation of acetate to acetyl CoA and in the secretion of acetate. It catalyzes the reaction ATP + acetate = ADP + acetyl phosphate. Some members of this family have been shown to act on propionate as well as acetate. An example of a propionate/acetate kinase is TdcD of E. coli (SP|P11868), an enzyme of an anaerobic pathway of threonine catabolism. It is not known how many members of this family act on additional substrates besides acetate.|
|References||DR PROSITE; PDOC00826;
RT Novel keto acid formate-lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L-threonine to propionate.
RA Hesslinger C, Fairhurst SA, Sawers G.
RL Mol Microbiol. 1998 Jan;27(2):477-92.
DR HAMAP; MF_00020; 241 of 243|
|Genome Property||GenProp0478: acetyl-CoA -- acetate interconversion via acetyl phosphate (HMM)|
| ||GenProp0754: acetate production from acetylphosphate (HMM)|
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