| Accession | TIGR00019 |
| Name | prfA |
| Function | peptide chain release factor 1 |
| Gene Symbol | prfA |
| Trusted Cutoff | 423.25 |
| Domain Trusted Cutoff | 423.25 |
| Noise Cutoff | 310.40 |
| Domain Noise Cutoff | 310.40 |
| Isology Type | equivalog |
| HMM Length | 361 |
| Mainrole Category | Protein synthesis |
| Subrole Category | Translation factors |
| Gene Ontology Term | GO:0003747: translation release factor activity molecular_function |
| | GO:0006415: translational termination biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:09PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM describes peptide chain release factor 1 (PrfA, RF-1), and excludes the related peptide chain release factor 2 (PrfB, RF-2). RF-1 helps recognize and terminate translation at UAA and UAG stop codons. The mitochondrial release factors are prfA-like, although not included above the trusted cutoff for this model. RF-1 does not have a translational frameshift. |
| References | SE TIGR
GA hmmsw
DR HAMAP; MF_00093; 498 of 505 |
| Genome Property | GenProp0746: translation termination, bacterial (HMM) |
| | GenProp0799: bacterial core gene set, exactly 1 per genome (HMM) |
