HMM Summary Page: TIGR00043
| Accession | TIGR00043 |
| Name | TIGR00043 |
| Function | probable rRNA maturation factor YbeY |
| Gene Symbol | ybeY |
| Trusted Cutoff | 42.05 |
| Domain Trusted Cutoff | 42.05 |
| Noise Cutoff | 38.05 |
| Domain Noise Cutoff | 38.05 |
| Isology Type | equivalog |
| HMM Length | 111 |
| Mainrole Category | Unknown function |
| Subrole Category | General |
| Gene Ontology Term | GO:0008150: biological_process biological_process |
| GO:0046872: metal ion binding molecular_function | |
| Author | Richardson DL, Haft DH |
| Entry Date | Apr 20 1999 2:04PM |
| Last Modified | Aug 13 2012 9:51AM |
| Comment | This metalloprotein family is represented by a single member sequence only in nearly every bacterium. Crystallography demonstrated metal-binding activity, possibly to nickel. It is a predicted to be a metallohydrolase, and more recently it was shown that mutants have a ribosomal RNA processing defect. |
| References | DR HAMAP; MF_00009; 511 of 518 RN [1] RM PMID:20807199 RT Role of Escherichia coli YbeY, a highly conserved protein, in rRNA processing. RA Davies BW, Kohrer C, Jacob AI, Simmons LA, Zhu J, Aleman LM, Rajbhandary UL, Walker GC RL Mol Microbiol. 2010 Oct;78(2):506-18. RN [2] RM PMID:16511207 RT The ybeY protein from Escherichia coli is a metalloprotein. RA Zhan C, Fedorov EV, Shi W, Ramagopal UA, Thirumuruhan R, Manjasetty BA, Almo SC, Fiser A, Chance MR, Fedorov AA RL Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Nov 1;61(Pt 11):959-63. Epub 2005 Oct 20. |
| Genome Property | GenProp0799: bacterial core gene set, exactly 1 per genome (HMM) |