| Accession | TIGR00055 |
| Name | uppS |
| Function | di-trans,poly-cis-decaprenylcistransferase |
| Gene Symbol | uppS |
| Trusted Cutoff | 109.55 |
| Domain Trusted Cutoff | 109.55 |
| Noise Cutoff | 25.10 |
| Domain Noise Cutoff | 25.10 |
| Isology Type | equivalog |
| EC Number | 2.5.1.31 |
| HMM Length | 228 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
| Gene Ontology Term | GO:0005737: cytoplasm cellular_component |
| | GO:0008834: di-trans,poly-cis-decaprenylcistransferase activity molecular_function |
| | GO:0009252: peptidoglycan biosynthetic process biological_process |
| Author | Richardson DL, Haft DH |
| Entry Date | Apr 20 1999 2:04PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components.
Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. |
| References | RN [1]
RM 98344035
RT Molecular cloning, expression, and purification of undecaprenyl diphosphate synthase. No sequence similarity between E- and Z-prenyl diphosphate synthases.
RA Shimizu N, Koyama T, Ogura K
RL J Biol Chem 1998 Jul 31;273(31):19476-81
RN [2]
RM 99102211
RT Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: cloning, expression, and characterization of the essential uppS gene.
RA Apfel CM, Takacs B, Fountoulakis M, Stieger M, Keck W
RL J Bacteriol 1999 Jan;181(2):483-92
SE TIGR
AL msa
DR HAMAP; MF_01139; 186 of 187 |
| Genome Property | GenProp0971: biosynthesis of undecaprenyl phosphate (Und-P) (HMM) |
