HMM Summary Page: TIGR00057

AccessionTIGR00057
NameTIGR00057
FunctiontRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family
Trusted Cutoff123.20
Domain Trusted Cutoff123.20
Noise Cutoff75.45
Domain Noise Cutoff75.45
Isology Typeequivalog
HMM Length202
Mainrole CategoryUnknown function
Subrole CategoryGeneral
AuthorRichardson DL, Haft DH
Entry DateApr 20 1999 2:04PM
Last ModifiedMay 7 2012 5:49PM
CommentHas paralogs, but YrdC called a tRNA modification protein. Ref 2 authors say probably heteromultimeric complex. Paralogs may mean its does the final binding to the tRNA.
ReferencesRN [1] RM PMID:22378793 RT Biosynthesis of Threonylcarbamoyl Adenosine (t6A), a Universal tRNA Nucleoside. RA Deutsch C, El Yacoubi B, de Crecy-Lagard V, Iwata-Reuyl D RL J Biol Chem. 2012 Apr 20;287(17):13666-73. RN [2] RM PMID:21775474 RT YrdC exhibits properties expected of a subunit for a tRNA threonylcarbamoyl transferase. RA Harris KA, Jones V, Bilbille Y, Swairjo MA, Agris PF RL RNA. 2011 Sep;17(9):1678-87. RN [3] RM PMID:1325384 RT Isolation and characterization of SUA5, a novel gene required for normal growth in Saccharomyces cerevisiae. RA Na JG, Pinto I, Hampsey M RL Genetics. 1992 Aug;131(4):791-801. AL msa DR HAMAP; MF_01852; 27 of 150
Genome PropertyGenProp1060: tRNA N6-threonylcarbamoyladenosine modification (HMM)
GenProp1060: tRNA N6-threonylcarbamoyladenosine modification (HMM)
GenProp1060: tRNA N6-threonylcarbamoyladenosine modification (HMM)