HMM Summary Page: TIGR00069

Functionhistidinol dehydrogenase
Gene SymbolhisD
Trusted Cutoff243.80
Domain Trusted Cutoff243.80
Noise Cutoff212.50
Domain Noise Cutoff212.50
Isology Typeequivalog_domain
EC Number1.1.1.23
HMM Length393
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryHistidine family
Gene Ontology TermGO:0000105: histidine biosynthetic process biological_process
GO:0004399: histidinol dehydrogenase activity molecular_function
AuthorRichardson DL, Selengut J
Entry DateApr 20 1999 2:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes a polypeptide sequence catalyzing the final step in histidine biosynthesis, found sometimes as an independent protein and sometimes as a part of a multifunctional protein.
ReferencesDR SWISSPROT; P06988; sample annotated sequence entry DR ECOCYC; EG10447; hisD DR PROSITE; PDOC00534; Histidinol dehydrogenase signature SE TIGR GA hmmls AL clustal DR HAMAP; MF_01024; 204 of 208
Genome PropertyGenProp0109: histidine biosynthesis from ribose-5-phosphate (HMM)