| Accession | TIGR00073 |
| Name | hypB |
| Function | hydrogenase accessory protein HypB |
| Gene Symbol | hypB |
| Trusted Cutoff | 121.20 |
| Domain Trusted Cutoff | 121.20 |
| Noise Cutoff | 85.40 |
| Domain Noise Cutoff | 85.40 |
| Isology Type | equivalog |
| HMM Length | 217 |
| Mainrole Category | Protein fate |
| Subrole Category | Protein modification and repair |
| Gene Ontology Term | GO:0000166: nucleotide binding molecular_function |
| | GO:0006464: protein modification process biological_process |
| | GO:0016530: metallochaperone activity molecular_function |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:08PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | A GTP hydrolase for assembly of nickel metallocenter of hydrogenase. A similar protein, ureG, is an accessory protein for urease, which also uses nickel.
hits scoring 75 and above are safe as orthologs. [SS 1/05/04 I changed the role_ID and process GO from protein folding to to protein modification, since a protein folding role has not been established, but HypB is implicated in insertion of nickel into the large subunit of NiFe hydrogenases.] |
| References | A2 hmmalign
SE TIGR
GA hmmsw
AL msa
BD build_dir/0070 |
| Genome Property | GenProp0177: nickel-dependent hydrogenase (HMM) |