HMM Summary Page: TIGR00092

FunctionGTP-binding protein YchF
Gene SymbolychF
Trusted Cutoff279.20
Domain Trusted Cutoff279.20
Noise Cutoff203.55
Domain Noise Cutoff203.55
Isology Typehypoth_equivalog
HMM Length368
Mainrole CategoryUnknown function
Subrole CategoryGeneral
Gene Ontology TermGO:0005525: GTP binding molecular_function
AuthorRichardson DL, Haft DH
Entry DateApr 20 1999 2:04PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis predicted GTP-binding protein is found in a single copy in every complete bacterial genome, and is found in Eukaryotes. A more distantly related protein, separated from this model, is found in the archaea. It is known to bind GTP and double-stranded nucleic acid. It is suggested to belong to a nucleoprotein complex and act as a translation factor.
ReferencesRN [1] RM 12837776 RT Crystal structure of the YchF protein reveals binding sites for GTP and nucleic acid. RA Teplyakov A, Obmolova G, Chu SY, Toedt J, Eisenstein E, Howard AJ, Gilliland GL. RL J Bacteriol. 2003 Jul;185(14):4031-7. RN [2] RM 11200227 RT Comparative genomics of prokaryotic GTP-binding proteins (the Era, Obg, EngA, ThdF (TrmE), YchF and YihA families) and their relationship to eukaryotic GTP-binding proteins (the DRG, ARF, RAB, RAN, RAS and RHO families). RA Mittenhuber G. RL J Mol Microbiol Biotechnol 2001 Jan;3(1):21-35
Genome PropertyGenProp0799: bacterial core gene set, exactly 1 per genome (HMM)