|Function||16S rRNA (guanine(527)-N(7))-methyltransferase RsmG|
|Domain Trusted Cutoff||99.50|
|Domain Noise Cutoff||75.90|
|Mainrole Category||Protein synthesis|
|Subrole Category||tRNA and rRNA base modification|
|Gene Ontology Term||GO:0005575: cellular_component cellular_component|
| ||GO:0008168: methyltransferase activity molecular_function|
| ||GO:0031167: rRNA methylation biological_process|
| ||GO:0046118: 7-methylguanosine biosynthetic process biological_process|
|Entry Date||Apr 20 1999 2:07PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||RsmG was previously called GidB (glucose-inhibited division protein B). It is present and a single copy in nearly all complete eubacterial genomes. It is missing only from some obligate intracellular species of various lineages (Chlamydiae, Ehrlichia, Wolbachia, Anaplasma, Buchnera, etc.). RsmG shows a methytransferase fold in its the crystal structure, and acts as a 7-methylguanosine (m(7)G) methyltransferase, apparently specific to 16S rRNA.|
RT Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria.
RA Okamoto S, Tamaru A, Nakajima C, Nishimura K, Tanaka Y, Tokuyama S, Suzuki Y, Ochi K
RT Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold.
RA Romanowski MJ, Bonanno JB, Burley SK.
RL Proteins. 2002 Jun 1;47(4):563-7.
DR HAMAP; MF_00074; 519 of 539|
|Genome Property||GenProp0802: ribosome biogenesis proteins, bacteria (HMM)|
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