HMM Summary Page: TIGR00143

AccessionTIGR00143
NamehypF
Functioncarbamoyltransferase HypF
Gene SymbolhypF
Trusted Cutoff466.10
Domain Trusted Cutoff466.10
Noise Cutoff359.80
Domain Noise Cutoff359.80
Isology Typeequivalog
HMM Length741
Mainrole CategoryProtein fate
Subrole CategoryProtein modification and repair
Gene Ontology TermGO:0003998: acylphosphatase activity molecular_function
GO:0003998: acylphosphatase activity molecular_function
GO:0003998: acylphosphatase activity molecular_function
GO:0006464: protein modification process biological_process
GO:0006464: protein modification process biological_process
GO:0006464: protein modification process biological_process
AuthorHaft DH, Richardson DL
Entry DateApr 20 1999 2:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentA previously described regulatory effect of HypF mutatation is attributable to loss of activity of a regulatory hydrogenase. A zinc finger-like region CXXCX(18)CXXCX(24)CXXCX(18)CXXC region further supported the regulatory hypothesis. However, more recent work (PUBMED:11375153) shows the direct effect is on the activity of expressed hydrogenases with nickel/iron centers, rather than on expression.
ReferencesRM 11375153 RT Transposon mutagenesis in purple sulfur photosynthetic bacteria: identification of hypF, encoding a protein capable of processing [NiFe] hydrogenases in alpha, beta, and gamma subdivisions of the proteobacteria. RA Fodor B, Rakhely G, Kovacs AT, Kovacs KL. RL Appl Environ Microbiol 2001 Jun;67(6):2476-83
Genome PropertyGenProp0177: nickel-dependent hydrogenase (HMM)
GenProp0177: nickel-dependent hydrogenase (HMM)
GenProp0177: nickel-dependent hydrogenase (HMM)
GenProp0177: nickel-dependent hydrogenase (HMM)
GenProp0177: nickel-dependent hydrogenase (HMM)
GenProp0177: nickel-dependent hydrogenase (HMM)