HMM Summary Page: TIGR00151

Function2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Gene SymbolispF
Trusted Cutoff116.45
Domain Trusted Cutoff116.45
Noise Cutoff42.35
Domain Noise Cutoff42.35
Isology Typeequivalog_domain
EC Number4.6.1.12
HMM Length155
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0008685: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity molecular_function
GO:0019288: isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway biological_process
AuthorHaft DH, Richardson DL
Entry DateApr 20 1999 2:05PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, the IspF protein of the deoxyxylulose (non-mevalonate) pathway of IPP biosynthesis. This protein occurs as an IspDF bifunctional fusion protein in about 20 percent of bacterial genomes.
ReferencesSE TIGR AL msa DR SWISS-PROT; P36663; annotated E. coli entry DR HAMAP; MF_01520; 79 of 79
Genome PropertyGenProp0048: IPP biosynthesis via deoxyxylulose (HMM)