HMM Summary Page: TIGR00187

Functionriboflavin synthase, alpha subunit
Gene SymbolribE
Trusted Cutoff156.60
Domain Trusted Cutoff156.60
Noise Cutoff116.95
Domain Noise Cutoff116.95
Isology Typeequivalog
EC Number2.5.1.9
HMM Length207
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryRiboflavin, FMN, and FAD
Gene Ontology TermGO:0004746: riboflavin synthase activity molecular_function
GO:0009231: riboflavin biosynthetic process biological_process
AuthorLoftus BJ
Entry DateApr 20 1999 2:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein family consists almost entirely of two lumazine-binding domains, described in the HMM Lum_binding from PFAM. The model generates lower scores against other proteins that also have two lumazine-binding domains, including some involved in bioluminescence. The name ribE was selected, from among alternatives including ribB and ribC, to match the usage in EcoCyc.
ReferencesA2 hmmalign DR ECOCYC; EG11406; ribE; DR PFAM; PF00677; Lum_binding; SE TIGR GA hmmls AL msa, belvu BD build_dir/0248
Genome PropertyGenProp0112: riboflavin, FAD and FMN from GTP and ribulose-5-P (HMM)