HMM Summary Page: TIGR00199
Accession | TIGR00199 |
Name | PncC_domain |
Function | amidohydrolase, PncC family |
Trusted Cutoff | 68.90 |
Domain Trusted Cutoff | 68.90 |
Noise Cutoff | 48.95 |
Domain Noise Cutoff | 48.95 |
Isology Type | subfamily_domain |
EC Number | 3.5.-.- |
HMM Length | 149 |
Mainrole Category | DNA metabolism |
Subrole Category | DNA replication, recombination, and repair |
Author | Loftus BJ, Haft DH |
Entry Date | Apr 20 1999 2:06PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | CinA is a DNA damage- or competence-inducible protein that is polycistronic with recA in a number of species. Several bacterial species have a protein consisting largely of the C-terminal domain of CinA but lacking the N-terminal domain, including nicotinamide mononucleotide (NMN) deamidase (3.5.1.42) proteins PncC in Shewanella oneidensis and ygaD in E. coli. |
References | DR INTERPRO; IPR003396 DR PFAM; PF02464; CinA SE TIGR DR HAMAP; MF_00226; 160 of 185 RN [1] RM PMID:21953451 RT Identification of nicotinamide mononucleotide deamidase of the bacterial pyridine nucleotide cycle reveals a novel broadly conserved amidohydrolase family. RA Galeazzi L, Bocci P, Amici A, Brunetti L, Ruggieri S, Romine M, Reed S, Osterman AL, Rodionov DA, Sorci L, Raffaelli N RL J Biol Chem. 2011 Nov 18;286(46):40365-75. |