HMM Summary Page: TIGR00213

FunctionD,D-heptose 1,7-bisphosphate phosphatase
Gene SymbolgmhB
Trusted Cutoff149.60
Domain Trusted Cutoff149.60
Noise Cutoff93.00
Domain Noise Cutoff93.00
Isology Typesubfamily
HMM Length176
Mainrole CategoryCell envelope
Subrole CategoryBiosynthesis and degradation of surface polysaccharides and lipopolysaccharides
AuthorHaft DH
Entry DateApr 20 1999 2:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family of proteins formerly designated yaeD resembles the histidinol phosphatase domain of the bifunctional protein HisB. The member from E. coli has been characterized as D,D-heptose 1,7-bisphosphate phosphatase, GmhB, involved in inner core LPS assembly (PMID:11751812).
ReferencesSE TIGR GA hmmsw RM 11751812 RT Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli. RA Kneidinger B, Marolda C, Graninger M, Zamyatina A, McArthur F, Kosma P, Valvano MA, Messner P. RL J Bacteriol. 2002 Jan;184(2):363-9.
Genome PropertyGenProp0203: LPS inner core biosynthesis, ketodeoxyoctonate and heptose type (HMM)