| Accession | TIGR00214 |
| Name | lipB |
| Function | lipoyl(octanoyl) transferase |
| Gene Symbol | lipB |
| Trusted Cutoff | 83.55 |
| Domain Trusted Cutoff | 83.55 |
| Noise Cutoff | 64.65 |
| Domain Noise Cutoff | 64.65 |
| Isology Type | equivalog |
| EC Number | 2.3.1.181 |
| HMM Length | 187 |
| Mainrole Category | Protein fate |
| Subrole Category | Protein modification and repair |
| Gene Ontology Term | GO:0009107: lipoate biosynthetic process biological_process |
| | GO:0016979: lipoate-protein ligase activity molecular_function |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:08PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Involved in lipoate biosynthesis as the main determinant of the lipoyl-protein ligase activity required for lipoylation of enzymes such as alpha-ketoacid dehydrogenases. Involved in activation and re-activation (following denaturation) of lipoyl-protein ligases (calcium ion-dependant process). |
| References | DR ECOCYC; EG11591;
DR PROSITE; PDOC01017;
SE TIGR
AL clustalw
RN [1]
RM 12591875
RT The Escherichia coli lipB gene encodes lipoyl (octanoyl)-acyl carrier protein:protein transferase.
RA Jordan SW, Cronan JE Jr.
DR HAMAP; MF_00013; 331 of 337 |
| Genome Property | GenProp0745: lipoyl-protein attachment (HMM) |
