| Accession | TIGR00228 |
| Name | ruvC |
| Function | crossover junction endodeoxyribonuclease RuvC |
| Gene Symbol | ruvC |
| Trusted Cutoff | 100.65 |
| Domain Trusted Cutoff | 100.65 |
| Noise Cutoff | 47.50 |
| Domain Noise Cutoff | 47.50 |
| Isology Type | equivalog |
| EC Number | 3.1.22.4 |
| HMM Length | 156 |
| Mainrole Category | DNA metabolism |
| Subrole Category | DNA replication, recombination, and repair |
| Gene Ontology Term | GO:0006310: DNA recombination biological_process |
| | GO:0008821: crossover junction endodeoxyribonuclease activity molecular_function |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:09PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Endonuclease that resolves Holliday junction intermediates in genetic recombination. The active form of the protein is a dimer. Structure studies reveals that the catalytic center, comprised of four acidic residues, lies at the bottom of a cleft that fits a DNA duplex. The model hits a single Synechocystis PCC6803 protein at a score of 30, below the trusted cutoff, that appears orthologous and may act as authentic RuvC. |
| References | DR ECOCYC; EG10925; ruvC;
SE TIGR
GA hmmls
AL clustalw
DR HAMAP; MF_00034; 375 of 393 |
| Genome Property | GenProp0198: ruvABC Holliday junction complex (HMM) |
