HMM Summary Page: TIGR00237

Functionexodeoxyribonuclease VII, large subunit
Gene SymbolxseA
Trusted Cutoff151.75
Domain Trusted Cutoff151.75
Noise Cutoff118.85
Domain Noise Cutoff118.85
Isology Typeequivalog
EC Number3.1.11.6
HMM Length432
Mainrole CategoryDNA metabolism
Subrole CategoryDegradation of DNA
Gene Ontology TermGO:0006308: DNA catabolic process biological_process
GO:0008855: exodeoxyribonuclease VII activity molecular_function
GO:0009318: exodeoxyribonuclease VII complex cellular_component
AuthorLoftus BJ
Entry DateApr 20 1999 2:10PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family consist of exodeoxyribonuclease VII, large subunit XseA which catalyses exonucleolytic cleavage in either the 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. Exonuclease VII consists of one large subunit and four small subunits.
ReferencesDR Swissprot; P04994; DR ECOCYC; EG11072; SE TIGR GA hmmls AL clustalw RM Medline: 6284744 RT Subunit structure of Escherichia coli exonuclease VII. RA Vales LD, Rabin BA, Chase JW. RL J Biol Chem. 1982 Aug 10;257(15):8799-805. DR HAMAP; MF_00378; 288 of 293
Genome PropertyGenProp1095: exodeoxyribonuclease VII (HMM)