HMM Summary Page: TIGR00239

Functionoxoglutarate dehydrogenase (succinyl-transferring), E1 component
Gene SymbolsucA
Trusted Cutoff770.00
Domain Trusted Cutoff770.00
Noise Cutoff618.85
Domain Noise Cutoff618.85
Isology Typeequivalog
EC Number1.2.4.2
HMM Length931
Mainrole CategoryEnergy metabolism
Subrole CategoryTCA cycle
Gene Ontology TermGO:0004591: oxoglutarate dehydrogenase (succinyl-transferring) activity molecular_function
GO:0006099: tricarboxylic acid cycle biological_process
GO:0006554: lysine catabolic process biological_process
GO:0006568: tryptophan metabolic process biological_process
GO:0045252: oxoglutarate dehydrogenase complex cellular_component
AuthorHaft DH
Entry DateApr 20 1999 2:03PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe 2-oxoglutarate dehydrogenase complex consists of this thiamine pyrophosphate-binding subunit (E1), dihydrolipoamide succinyltransferase (E2), and lipoamide dehydrogenase (E3). The E1 ortholog from Corynebacterium glutamicum is unusual in having an N-terminal extension that resembles the dihydrolipoamide succinyltransferase (E2) component of 2-oxoglutarate dehydrogenase.
References DR HAMAP; MF_01169; 43 of 43
Genome PropertyGenProp0630: 2-oxoglutarate dehydrogenase system (HMM)