HMM Summary Page: TIGR00259

Functionmembrane complex biogenesis protein, BtpA family
Trusted Cutoff153.40
Domain Trusted Cutoff153.40
Noise Cutoff106.15
Domain Noise Cutoff106.15
Isology Typesubfamily
HMM Length257
Mainrole CategoryProtein fate
Subrole CategoryProtein folding and stabilization
AuthorHaft DH
Entry DateApr 20 1999 2:05PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are found in C. elegans, Synechocystis sp., E. coli, and several of the Archaea. Members in Cyanobacteria have been shown to play a role in protein complex biogenesis, and designated BtpA (biogenesis of thylakoid protein). Homologs in non-photosynthetic species, where thylakoid intracytoplasmic membranes are lacking, are likely to act elsewhere in membrane protein biogenesis.
ReferencesRN [1] RM PMID:9045660 RT Molecular identification of a novel protein that regulates biogenesis of photosystem I, a membrane protein complex. RA Bartsevich VV, Pakrasi HB RL J Biol Chem. 1997 Mar 7;272(10):6382-7. RN [2] RM PMID:12651001 RT Purification of recombinant BtpA and Ycf3, proteins involved in membrane protein biogenesis in Synechocystis PCC 6803. RA Schwabe TM, Gloddek K, Schluesener D, Kruip J RL J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Mar 25;786(1-2):45-59.