Accession | TIGR00272 |
Name | DPH2 |
Function | diphthamide biosynthesis protein 2 |
Trusted Cutoff | 184.05 |
Domain Trusted Cutoff | 184.05 |
Noise Cutoff | 146.75 |
Domain Noise Cutoff | 146.75 |
Isology Type | equivalog |
HMM Length | 497 |
Mainrole Category | Protein fate |
Subrole Category | Protein modification and repair |
Gene Ontology Term | GO:0017183: peptidyl-diphthamide biosynthetic process from peptidyl-histidine biological_process |
Author | Haft DH |
Entry Date | Dec 8 1999 11:17AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This protein has been shown in Saccharomyces cerevisiae to be one of several required for the modification of a particular histidine residue of translation elongation factor 2 to diphthamide. This modified site can then become the target for ADP-ribosylation by diphtheria toxin. |
References | A2 hmmalign
GA hmmsearch
SE TIGR |