| Accession | TIGR00272 |
| Name | DPH2 |
| Function | diphthamide biosynthesis protein 2 |
| Trusted Cutoff | 184.05 |
| Domain Trusted Cutoff | 184.05 |
| Noise Cutoff | 146.75 |
| Domain Noise Cutoff | 146.75 |
| Isology Type | equivalog |
| HMM Length | 497 |
| Mainrole Category | Protein fate |
| Subrole Category | Protein modification and repair |
| Gene Ontology Term | GO:0017183: peptidyl-diphthamide biosynthetic process from peptidyl-histidine biological_process |
| Author | Haft DH |
| Entry Date | Dec 8 1999 11:17AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This protein has been shown in Saccharomyces cerevisiae to be one of several required for the modification of a particular histidine residue of translation elongation factor 2 to diphthamide. This modified site can then become the target for ADP-ribosylation by diphtheria toxin. |
| References | A2 hmmalign
GA hmmsearch
SE TIGR |
