HMM Summary Page: TIGR00291
| Accession | TIGR00291 |
| Name | RNA_SBDS |
| Function | rRNA metabolism protein, SBDS family |
| Trusted Cutoff | 126.55 |
| Domain Trusted Cutoff | 126.55 |
| Noise Cutoff | 104.45 |
| Domain Noise Cutoff | 104.45 |
| Isology Type | equivalog |
| HMM Length | 231 |
| Mainrole Category | Protein synthesis |
| Subrole Category | Other |
| Gene Ontology Term | GO:0003723: RNA binding molecular_function |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:05PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This protein family, possibly universal in both archaea and eukaryotes, appears to be involved in (ribosomal) RNA metabolism. Mutations in the human ortholog are associated with Shwachman-Bodian-Diamond syndrome. |
| References | RN [1] RM PMID:15701634 RT The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. RA Savchenko A, Krogan N, Cort JR, Evdokimova E, Lew JM, Yee AA, Sanchez-Pulido L, Andrade MA, Bochkarev A, Watson JD, Kennedy MA, Greenblatt J, Hughes T, Arrowsmith CH, Rommens JM, Edwards AM RL J Biol Chem. 2005 May 13;280(19):19213-20. Epub 2005 Feb 8. DR PROSITE; PS01267; |
| Genome Property | GenProp0831: archaeal core gene set, exactly 1 per genome (HMM) |