| Accession | TIGR00305 |
| Name | TIGR00305 |
| Function | putative toxin-antitoxin system toxin component, PIN family |
| Trusted Cutoff | 29.15 |
| Domain Trusted Cutoff | 29.15 |
| Noise Cutoff | 28.85 |
| Domain Noise Cutoff | 28.85 |
| Isology Type | equivalog |
| HMM Length | 115 |
| Mainrole Category | Cellular processes |
| Subrole Category | Other |
| Gene Ontology Term | GO:0004521: endoribonuclease activity molecular_function |
| | GO:0005515: protein binding molecular_function |
| Author | Loftus BJ, Haft DH |
| Entry Date | Apr 20 1999 2:05PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This uncharacterized protein family, part of the PIN domain superfamily, is restricted to bacteria and archaea. A comprehensive in silico study of toxin-antitoxin systems by Makarova, et al. (2009) finds evidence this family represents the toxin-like component of one class of type 2 toxin-antitoxin systems. |
| References | DR PFAM; PF01850; PIN domain
RN [1]
RM PMID:19493340
RT Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes.
RA Makarova KS, Wolf YI, Koonin EV
RL Biol Direct. 2009 Jun 3;4:19. |
| Genome Property | GenProp0321: addiction modules (HMM) |