| Accession | TIGR00317 |
| Name | cobS |
| Function | cobalamin 5'-phosphate synthase |
| Gene Symbol | cobS |
| Trusted Cutoff | 110.00 |
| Domain Trusted Cutoff | 110.00 |
| Noise Cutoff | 87.10 |
| Domain Noise Cutoff | 87.10 |
| Isology Type | equivalog |
| EC Number | 2.7.8.26 |
| HMM Length | 241 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Heme, porphyrin, and cobalamin |
| Gene Ontology Term | GO:0008818: cobalamin 5'-phosphate synthase activity molecular_function |
| | GO:0009236: cobalamin biosynthetic process biological_process |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:06PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | cobS is involved with cobalamin biosynthesis in part III of colbalmin biosynthesis. The enzyme catyalzes the reactions adenosylcobinamide-GDP + alpha-ribazole-5'-P = adenosylcobalamin-5'-phosphate + GMP and adenosylcobinamide-GDP + alpha-ribazole = adenosylcobalamin + GMP. The protein product is associated with a large complex of proteins and is induced by cobinamide. |
| References | DR ECOCYC; EG12150; cobS;
DR SWISSPROT; Q05602;
RM 93273696
RT Characterization of the cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimurium.
SE TIGR
GA hmmls
AL clustalw, belvu
DR HAMAP; MF_00719; 118 of 150 |
| Genome Property | GenProp0269: coenzyme B12 biosynthesis from cob(II)yrinate diamide (HMM) |
