|Function||fructose-1,6-bisphosphatase, class II|
|Domain Trusted Cutoff||259.30|
|Domain Noise Cutoff||213.35|
|Mainrole Category||Energy metabolism|
|Subrole Category||Pentose phosphate pathway|
|Gene Ontology Term||GO:0006094: gluconeogenesis biological_process|
| ||GO:0042132: fructose 1,6-bisphosphate 1-phosphatase activity molecular_function|
|Author||Haft DH, Loftus BJ|
|Entry Date||Apr 20 1999 2:07PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||This model represents GlpX, one of three classes of bacterial fructose-1,6-bisphosphatases. This form is homodimeric and Mn2+-dependent, and only very distantly related to the class I fructose-1,6-bisphosphatase, the product of the fbp gene, which is homotetrameric and Mg2+-dependent. A third class is found as one of two types in Bacillus subtilis.
In E. coli, GlpX is found in the glpFKX operon together with a glycerol update protein and glycerol kinase.|
|References||DR ECOGENE; EG11517; glpX;
RT Purification and characterization of glpX-encoded fructose 1, 6-bisphosphatase, a new enzyme of the glycerol 3-phosphate regulon of Escherichia coli.
RA Donahue JL, Bownas JL, Niehaus WG, Larson TJ.
RL J Bacteriol 2000 Oct;182(19):5624-7
DR EXPERIMENTAL; OMNI|NTL01EC03831; Escherichia coli
DR EXPERIMENTAL; GP|1753218; Synechocystis sp. PCC 6803|
|Genome Property||GenProp0120: pentose phosphate cycle (HMM)|
© J. Craig Venter Institute | Privacy Statement | Data Disclaimer