HMM Summary Page: TIGR00334
| Accession | TIGR00334 |
| Name | 5S_RNA_mat_M5 |
| Function | ribonuclease M5 |
| Gene Symbol | rnmV |
| Trusted Cutoff | 110.65 |
| Domain Trusted Cutoff | 110.65 |
| Noise Cutoff | 61.85 |
| Domain Noise Cutoff | 61.85 |
| Isology Type | equivalog |
| EC Number | 3.1.26.8 |
| HMM Length | 174 |
| Mainrole Category | Transcription |
| Subrole Category | RNA processing |
| Gene Ontology Term | GO:0006364: rRNA processing biological_process |
| GO:0043822: ribonuclease M5 activity molecular_function | |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:09PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This family of orthologous proteins shows a weak but significant similarity to the central region of the DnaG-type DNA primase. The region of similarity is termed the Toprim (topoisomerase-primase) domain and is also shared by RecR, OLD family nucleases, and type IA and II topoisomerases. |
| References | RN [1] RM PMID:16077031 RT The 5S rRNA maturase, ribonuclease M5, is a Toprim domain family member. RA Allemand F, Mathy N, Brechemier-Baey D, Condon C RL Nucleic Acids Res. 2005 Aug 2;33(13):4368-76 RN [2] RM 98391745 RT Toprim--a conserved catalytic domain in type IA and II topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins. RA Aravind L, Leipe DD, Koonin EV RL Nucleic Acids Res 1998 Sep 15;26(18):4205-13 SE TIGR GA hmmls |