| Accession | TIGR00339 |
| Name | sopT |
| Function | sulfate adenylyltransferase |
| Gene Symbol | sat |
| Trusted Cutoff | 322.95 |
| Domain Trusted Cutoff | 322.95 |
| Noise Cutoff | 181.80 |
| Domain Noise Cutoff | 181.80 |
| Isology Type | equivalog_domain |
| EC Number | 2.7.7.4 |
| HMM Length | 383 |
| Mainrole Category | Central intermediary metabolism |
| Subrole Category | Sulfur metabolism |
| Gene Ontology Term | GO:0004781: sulfate adenylyltransferase (ATP) activity molecular_function |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:09PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme forms adenosine 5'-phosphosulfate (APS) from ATP and free sulfate, the first step in the formation of the activated sulfate donor 3'-phosphoadenylylsulfate (PAPS). In some cases, it is found in a bifunctional protein in which the other domain, APS kinase, catalyzes the second and final step, the phosphorylation of APS to PAPS; the combined ATP sulfurylase/APS kinase may be called PAPS synthase.
Members of this family also include the dissimilatory sulfate adenylyltransferase (sat) of the sulfate reducer Archaeoglobus fulgidus. |
| References | RM 96094345
RT The isolation and characterization of cDNA encoding the mouse bifunctional ATP sulfurylase-adenosine 5'-phosphosulfate kinase.
RA Li H, Deyrup A, Mensch JR Jr, Domowicz M, Konstantinidis AK, Schwartz NB
RL J Biol Chem 1995 Dec 8;270(49):29453-9
SE TIGR
GA hmmls
AL clustalw
DR HAMAP; MF_00066; 58 of 59 |
| Genome Property | GenProp0149: sulfate reduction to sulfide, assimilatory (HMM) |
| | GenProp0149: sulfate reduction to sulfide, assimilatory (HMM) |
| | GenProp0155: dissimilatory sulfate reduction (HMM) |