| Accession | TIGR00348 |
| Name | hsdR |
| Function | type I site-specific deoxyribonuclease, HsdR family |
| Gene Symbol | hsdR |
| Trusted Cutoff | 284.55 |
| Domain Trusted Cutoff | 284.55 |
| Noise Cutoff | 213.45 |
| Domain Noise Cutoff | 213.45 |
| Isology Type | subfamily |
| EC Number | 3.1.21.3 |
| HMM Length | 674 |
| Mainrole Category | DNA metabolism |
| Subrole Category | Restriction/modification |
| Gene Ontology Term | GO:0009035: Type I site-specific deoxyribonuclease activity molecular_function |
| | GO:0009307: DNA restriction-modification system biological_process |
| | GO:0019812: Type I site-specific deoxyribonuclease complex cellular_component |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:08PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This gene is part of the type I restriction and modification system which is composed of three polypeptides R (restriction endonuclease), M (modification) and S (specificity). This group of enzymes recognize specific short DNA sequences and have an absolute requirement for ATP (or dATP) and S-adenosyl-L-methionine. They also catalyse the reactions of EC 2.1.1.72 and EC 2.1.1.73, with similar site specificity.(J. Mol. Biol. 271 (3), 342-348 (1997)).
Members of this family are assumed to differ from each other in DNA site specificity. |
| References | A2 hmmalign
DR EGAD:10320,
SE TIGR
GA hmmls |
