Accession | TIGR00355 |
Name | purH |
Function | phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase |
Gene Symbol | purH |
Trusted Cutoff | 528.00 |
Domain Trusted Cutoff | 528.00 |
Noise Cutoff | 462.65 |
Domain Noise Cutoff | 462.65 |
Isology Type | equivalog |
EC Number | 2.1.2.3 3.5.4.10 |
HMM Length | 511 |
Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
Subrole Category | Purine ribonucleotide biosynthesis |
Gene Ontology Term | GO:0003937: IMP cyclohydrolase activity molecular_function |
| GO:0004643: phosphoribosylaminoimidazolecarboxamide formyltransferase activity molecular_function |
| GO:0009152: purine ribonucleotide biosynthetic process biological_process |
Author | Loftus BJ, Haft DH |
Entry Date | Apr 20 1999 2:09PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | PurH is bifunctional: IMP cyclohydrolase (EC 3.5.4.10); phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Involved in purine ribonucleotide biosynthesis. The IMP cyclohydrolase activity is in the N-terminal region. |
References | DR ECOCYC; EG10795; purH;
DR SWISSPROT; P15639;
SE TIGR
GA hmmls
AL clustalw, belvu
DR HAMAP; MF_00139; 305 of 310 |
Genome Property | GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM) |
| GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM) |