HMM Summary Page: TIGR00355

AccessionTIGR00355
NamepurH
Functionphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
Gene SymbolpurH
Trusted Cutoff528.00
Domain Trusted Cutoff528.00
Noise Cutoff462.65
Domain Noise Cutoff462.65
Isology Typeequivalog
EC Number2.1.2.3 3.5.4.10
HMM Length511
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryPurine ribonucleotide biosynthesis
Gene Ontology TermGO:0003937: IMP cyclohydrolase activity molecular_function
GO:0003937: IMP cyclohydrolase activity molecular_function
GO:0004643: phosphoribosylaminoimidazolecarboxamide formyltransferase activity molecular_function
GO:0004643: phosphoribosylaminoimidazolecarboxamide formyltransferase activity molecular_function
GO:0009152: purine ribonucleotide biosynthetic process biological_process
GO:0009152: purine ribonucleotide biosynthetic process biological_process
AuthorLoftus BJ, Haft DH
Entry DateApr 20 1999 2:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentPurH is bifunctional: IMP cyclohydrolase (EC 3.5.4.10); phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) Involved in purine ribonucleotide biosynthesis. The IMP cyclohydrolase activity is in the N-terminal region.
ReferencesDR ECOCYC; EG10795; purH; DR SWISSPROT; P15639; SE TIGR GA hmmls AL clustalw, belvu DR HAMAP; MF_00139; 305 of 310
Genome PropertyGenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM)
GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM)
GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM)
GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM)