|Function||queuosine biosynthesis protein QueC|
|Domain Trusted Cutoff||150.30|
|Domain Noise Cutoff||86.20|
|Mainrole Category||Unknown function|
|Author||Loftus BJ, Haft DH|
|Entry Date||Apr 20 1999 2:05PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||Members of this protein family are QueC, involved in synthesizing pre-Q0 from GTP en route to tRNA modification with queuosine. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In Rhizobium meliloti, the gene was designated exsB, possibly because of polar effects on exsA expression in a shared polycistronic mRNA. In Arthrobacter viscosus, the homologous gene was designated ALU1 and was associated with an aluminum tolerance phenotype.|
RT Genetic analysis identifies a function for the queC (ybaX) gene product at an initial step in the queuosine biosynthetic pathway in Escherichia coli.
RA Gaur R, Varshney U
RL J Bacteriol. 2005 Oct;187(20):6893-901.
RM PMID: 14660578
RT Identification of four genes necessary for biosynthesis of the modified nucleoside queuosine.
RA Reader JS, Metzgar D, Schimmel P, de Crecy-Lagard V
RL J Biol Chem. 2004 Feb 20;279(8):6280-5.
RT Functional analysis of exsC and exsB in regulation of exoenzyme S production by Pseudomonas aeruginosa.
RA Goranson J, Hovey AK, Frank DW.
RL J Bacteriol 1997 Mar;179(5):1646-54
RT Isolation of ALU1-P gene encoding a protein with aluminum tolerance activity from Arthrobacter viscosus.
RA Jo J, Jang YS, Kim KY, Kim MH, Kim IJ, Chung WI
RL Biochem Biophys Res Commun 1997 Oct 29;239(3):835-9
AL clustalw, belvu
DR HAMAP; MF_01633; 386 of 392|
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