| Accession | TIGR00380 |
| Name | cobD |
| Function | cobalamin biosynthesis protein CobD |
| Gene Symbol | cobD |
| Trusted Cutoff | 165.90 |
| Domain Trusted Cutoff | 165.90 |
| Noise Cutoff | 148.20 |
| Domain Noise Cutoff | 148.20 |
| Isology Type | equivalog |
| EC Number | 6.3.1.10 |
| HMM Length | 305 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Heme, porphyrin, and cobalamin |
| Gene Ontology Term | GO:0009236: cobalamin biosynthetic process biological_process |
| | GO:0016880: acid-ammonia (or amide) ligase activity molecular_function |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:06PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This protein is involved in cobalamin (vitamin B12) biosynthesis and porphyrin biosynthesis. It converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. It is part of the cob operon. |
| References | RN [1]
RM 96146525
RT Salmonella typhimurium cobalamin (vitamin B12) biosynthetic genes: functional studies in S. typhimurium and Escherichia coli.
RN [2]
RM 95362677
RT Identification and sequence analysis of genes involved in late steps in cobalamin (vitamin B12) synthesis in Rhodobacter capsulatus.
DR SWISSPROT; Q05600;
SE TIGR
GA hmmls
DR HAMAP; MF_00024; 47 of 48 |
| Genome Property | GenProp0269: coenzyme B12 biosynthesis from cob(II)yrinate diamide (HMM) |