HMM Summary Page: TIGR00381

FunctionCO dehydrogenase/acetyl-CoA synthase, delta subunit
Gene SymbolcdhD
Trusted Cutoff252.90
Domain Trusted Cutoff252.90
Noise Cutoff197.55
Domain Noise Cutoff197.55
Isology Typeequivalog
EC Number1.2.99.2
HMM Length389
Mainrole CategoryEnergy metabolism
Subrole CategoryChemoautotrophy
Gene Ontology TermGO:0006085: acetyl-CoA biosynthetic process biological_process
GO:0008168: methyltransferase activity molecular_function
GO:0018492: carbon-monoxide dehydrogenase (acceptor) activity molecular_function
AuthorLoftus BJ
Entry DateApr 20 1999 2:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis is the small subunit of a heterodimer which catalyzes the reaction CO + H2O + Acceptor = CO2 + Reduced acceptor and is involved in the synthesis of acetyl-CoA from CO2 and H2.
ReferencesRN [1] RM 96134964 RT Characterization of the cdhD and cdhE genes encoding subunits of the corrinoid/iron-sulfur enzyme of the CO dehydrogenase complex from Methanosarcina thermophila. RA Maupin-Furlow J, Ferry JG RL J Bacteriol 1996 Jan;178(2):340-6 RN [2] RT Cloning and expression of the gene cluster encoding key proteins involved in acetyl-CoA synthesis in Clostridium thermoaceticum: CO dehydrogenase, the corrinoid/Fe-S protein, and methyltransferase. RA Roberts DL, James-Hagstrom JE, Garvin DK, Gorst CM, Runquist JA, Baur JR, Haase FC, Ragsdale SW RL Proc Natl Acad Sci U S A 1989 Jan;86(1):32-6 SE TIGR GA hmmls AL clustalw, belvu DR HAMAP; MF_01135; 9 of 9