HMM Summary Page: TIGR00395

Functionleucine--tRNA ligase
Gene SymbolleuS
Trusted Cutoff648.50
Domain Trusted Cutoff648.50
Noise Cutoff373.75
Domain Noise Cutoff373.75
Isology Typeequivalog
EC Number6.1.1.4
HMM Length938
Mainrole CategoryProtein synthesis
Subrole CategorytRNA aminoacylation
Gene Ontology TermGO:0004823: leucine-tRNA ligase activity molecular_function
GO:0006429: leucyl-tRNA aminoacylation biological_process
AuthorHaft DH
Entry DateApr 20 1999 2:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe leucyl-tRNA synthetases belong to two families so broadly different that they are represented by separate models. This model includes both archaeal and cytosolic eukaryotic leucyl-tRNA synthetases; the eubacterial and mitochondrial forms differ so substantially that some other tRNA ligases score higher by this model than does any eubacterial LeuS.
ReferencesSE TIGR GA hmmls DR HAMAP; MF_00049; 29 of 550
Genome PropertyGenProp0258: tRNA aminoacylation (HMM)