| Accession | TIGR00405 |
| Name | KOW_elon_Spt5 |
| Function | transcription elongation factor Spt5 |
| Trusted Cutoff | 69.95 |
| Domain Trusted Cutoff | 69.95 |
| Noise Cutoff | 49.85 |
| Domain Noise Cutoff | 49.85 |
| Isology Type | equivalog |
| HMM Length | 145 |
| Mainrole Category | Protein synthesis |
| Subrole Category | Ribosomal proteins: synthesis and modification |
| Gene Ontology Term | GO:0003735: structural constituent of ribosome molecular_function |
| | GO:0006412: translation biological_process |
| | GO:0022625: cytosolic large ribosomal subunit cellular_component |
| Author | Haft DH, Loftus BJ |
| Entry Date | Apr 20 1999 2:09PM |
| Last Modified | Sep 16 2014 4:02PM |
| Comment | This protein contains a KOW domain, shared by bacterial NusG and the uL24 (previously L24p/L26e) family of ribosomal proteins. The most recent papers and crystal structures make this a transcription elongation factor rather than a ribosomal protein. |
| References | DR PFAM; PF00467;
RN [1]
RM PMID:20197319
RT Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif.
RA Hirtreiter A, Damsma GE, Cheung AC, Klose D, Grohmann D, Vojnic E, Martin AC, Cramer P, Werner F
RL Nucleic Acids Res. 2010 Jul;38(12):4040-51. |
| Genome Property | GenProp0831: archaeal core gene set, exactly 1 per genome (HMM) |
