HMM Summary Page: TIGR00415

Functionserine--tRNA ligase
Gene SymbolserS
Trusted Cutoff489.55
Domain Trusted Cutoff489.55
Noise Cutoff166.60
Domain Noise Cutoff166.60
Isology Typeequivalog
EC Number6.1.1.11
HMM Length518
Mainrole CategoryProtein synthesis
Subrole CategorytRNA aminoacylation
Gene Ontology TermGO:0004828: serine-tRNA ligase activity molecular_function
GO:0006434: seryl-tRNA aminoacylation biological_process
AuthorHaft DH
Entry DateApr 20 1999 2:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe seryl-tRNA synthetases from a few of the Archaea, represented by this model, are very different from the set of mutually more closely related seryl-tRNA synthetases from Eubacteria, Eukaryotes, and other Archaea. Although distantly homologous, the present set differs enough not to be recognized by the pfam HMM tRNA-synt_2b that recognizes the remainder of seryl-tRNA synthetases among oither class II amino-acyl tRNA synthetases.
ReferencesRM 99069316 RL J Bacteriol 1998 Dec;180(24):6446-9; RT Sequence divergence of seryl-tRNA synthetases in archaea.; RA Kim Hs, Vothknecht UC, Hedderich R, Celic I, Soll D; SE TIGR GA hmmls AL clustalw DR HAMAP; MF_01278; 4 of 7
Genome PropertyGenProp0258: tRNA aminoacylation (HMM)