HMM Summary Page: TIGR00418

Functionthreonine--tRNA ligase
Gene SymbolthrS
Trusted Cutoff383.65
Domain Trusted Cutoff383.65
Noise Cutoff288.75
Domain Noise Cutoff288.75
Isology Typeequivalog
EC Number6.1.1.3
HMM Length565
Mainrole CategoryProtein synthesis
Subrole CategorytRNA aminoacylation
Gene Ontology TermGO:0004829: threonine-tRNA ligase activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0006435: threonyl-tRNA aminoacylation biological_process
AuthorHaft DH
Entry DateApr 20 1999 2:10PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents the threonyl-tRNA synthetase found in most organisms. This protein is a class II tRNA synthetase, and is recognized by the pfam HMM tRNA-synt_2b. Note that B. subtilis has closely related isozymes thrS and thrZ. The N-terminal regions are quite dissimilar between archaeal and eubacterial forms, while some eukaryotic forms are missing sequence there altogether. .
ReferencesSE TIGR GA hmmls DR HAMAP; MF_00184; 462 of 475
Genome PropertyGenProp0258: tRNA aminoacylation (HMM)
GenProp0799: bacterial core gene set, exactly 1 per genome (HMM)