HMM Summary Page: TIGR00436

FunctionGTP-binding protein Era
Gene Symbolera
Trusted Cutoff116.25
Domain Trusted Cutoff116.25
Noise Cutoff95.25
Domain Noise Cutoff95.25
Isology Typeequivalog
HMM Length270
Mainrole CategoryProtein synthesis
Subrole CategoryOther
Gene Ontology TermGO:0003924: GTPase activity molecular_function
GO:0005525: GTP binding molecular_function
GO:0019843: rRNA binding molecular_function
GO:0042254: ribosome biogenesis biological_process
GO:0043022: ribosome binding molecular_function
AuthorLoftus BJ, Haft DH
Entry DateApr 20 1999 2:07PM
Last ModifiedFeb 14 2011 3:27PM
CommentEra is an essential GTPase in Escherichia coli and many other bacteria. It plays a role in ribosome biogenesis. Few bacteria lack this protein.
ReferencesSE TIGR RN [1] RM 99342029 RT Crystal structure of ERA: a GTPase-dependent cell cycle regulator containing an RNA binding motif. RA Chen X, Court DL, Ji X RL Proc Natl Acad Sci U S A 1999 Jul 20;96(15):8396-401 RN [2] RM 99458620 RT Era, an essential Escherichia coli small G-protein, binds to the 30S ribosomal subunit. RA Sayed A, Matsuyama Si, Inouye M RL Biochem Biophys Res Commun 1999 Oct 14;264(1):51-4 DR Swissprot; P06616; DR ECOCYC; EG10270; DR Swissprot; Q49768; DR HAMAP; MF_00367; 209 of 212
Genome PropertyGenProp0799: bacterial core gene set, exactly 1 per genome (HMM)
GenProp0802: ribosome biogenesis proteins, bacteria (HMM)