| Accession | TIGR00440 |
| Name | glnS |
| Function | glutamine--tRNA ligase |
| Gene Symbol | glnS |
| Trusted Cutoff | 425.80 |
| Domain Trusted Cutoff | 425.80 |
| Noise Cutoff | 343.00 |
| Domain Noise Cutoff | 343.00 |
| Isology Type | equivalog |
| EC Number | 6.1.1.18 |
| HMM Length | 524 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA aminoacylation |
| Gene Ontology Term | GO:0004819: glutamine-tRNA ligase activity molecular_function |
| | GO:0005737: cytoplasm cellular_component |
| | GO:0006425: glutaminyl-tRNA aminoacylation biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:07PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This protein is a relatively rare aminoacyl-tRNA synthetase, found in the cytosolic compartment of eukaryotes, in E. coli and a number of other Gram-negative Bacteria, and in Deinococcus radiodurans. In contrast, the pathway to Gln-tRNA in mitochondria, Archaea, Gram-positive Bacteria, and a number of other lineages is by misacylation with Glu followed by transamidation to correct the aminoacylation to Gln. This enzyme is a class I tRNA synthetase (hit by the pfam HMM tRNA-synt_1c) and is quite closely related to glutamyl-tRNA synthetases. |
| References | SE TIGR
GA hmmls
AL clustalw
DR HAMAP; MF_00126; 69 of 70 |
| Genome Property | GenProp0189: tRNA-Gln direct aminoacylation (HMM) |
| | GenProp0258: tRNA aminoacylation (HMM) |
