HMM Summary Page: TIGR00452

FunctiontRNA (mo5U34)-methyltransferase
Gene SymbolcmoB
Trusted Cutoff275.00
Domain Trusted Cutoff275.00
Noise Cutoff150.00
Domain Noise Cutoff150.00
Isology Typeequivalog
EC Number2.1.1.-
HMM Length316
Mainrole CategoryUnknown function
Subrole CategoryEnzymes of unknown specificity
AuthorLoftus BJ, Haft DH
Entry DateApr 20 1999 2:06PM
Last ModifiedDec 7 2011 5:41PM
CommentThis model describes CmoB, the enzyme tRNA (mo5U34)-methyltransferase involved in tRNA wobble base modification.
ReferencesRN [1] RM PMID:15383682 RT The modified wobble nucleoside uridine-5-oxyacetic acid in tRNAPro(cmo5UGG) promotes reading of all four proline codons in vivo. RA Nasvall SJ, Chen P, Bjork GR RL RNA. 2004 Oct;10(10):1662-73. DR HAMAP; MF_01590; 103 of 124
Genome PropertyGenProp1077: tRNA(Pro) cmo5UGG modification (HMM)