HMM Summary Page: TIGR00452

AccessionTIGR00452
NameTIGR00452
FunctiontRNA (mo5U34)-methyltransferase
Gene SymbolcmoB
Trusted Cutoff344.90
Domain Trusted Cutoff344.90
Noise Cutoff229.90
Domain Noise Cutoff229.90
Isology Typeequivalog
EC Number2.1.1.-
HMM Length314
Mainrole CategoryUnknown function
Subrole CategoryEnzymes of unknown specificity
AuthorLoftus BJ, Haft DH
Entry DateApr 20 1999 2:06PM
Last ModifiedDec 7 2011 5:41PM
CommentThis model describes a set of proteins with homology in its central region to a large number of methyltransferases active on a variety of substrates. The similarity includes a motif resembling ILDVGCG[SG]G. Known examples to date are restricted to the proteobacteria.
ReferencesRN [1] RM PMID:15383682 RT The modified wobble nucleoside uridine-5-oxyacetic acid in tRNAPro(cmo5UGG) promotes reading of all four proline codons in vivo. RA Nasvall SJ, Chen P, Bjork GR RL RNA. 2004 Oct;10(10):1662-73. DR HAMAP; MF_01590; 103 of 124
Genome PropertyGenProp1077: tRNA(Pro) cmo5UGG modification (HMM)