Accession | TIGR00461 |
Name | gcvP |
Function | glycine dehydrogenase |
Gene Symbol | gcvP |
Trusted Cutoff | 859.20 |
Domain Trusted Cutoff | 859.20 |
Noise Cutoff | 664.70 |
Domain Noise Cutoff | 664.70 |
Isology Type | equivalog |
EC Number | 1.4.4.2 |
HMM Length | 939 |
Mainrole Category | Energy metabolism |
Subrole Category | Amino acids and amines |
Gene Ontology Term | GO:0004375: glycine dehydrogenase (decarboxylating) activity molecular_function |
| GO:0019464: glycine decarboxylation via glycine cleavage system biological_process |
Author | Loftus BJ |
Entry Date | Apr 20 1999 2:07PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This apparently ubiquitous enzyme is found in bacterial, mammalian and plant sources. The enzyme catalyzes the reaction: GLYCINE + LIPOYLPROTEIN = S-AMINOMETHYL-DIHYDROLIPOYLPROTEIN + CO2. It is part of the glycine decarboxylase multienzyme complex (GDC) consisting of four proteins P, H, L and T. Active site in E.coli is located as the (K) residues at position 713 of the SEED alignment. |
References | DR Swissprot; P33195;
RM Medline 94237484;
DR ECOCYC; EG11810;
DR Swissprot; P49361;
RM MEDLINE; 94218395;
SE TIGR
GA hmmls
DR PFAM; PF02347
DR InterPro; IPR003437
DR HAMAP; MF_00711; 177 of 179 |