| Accession | TIGR00470 |
| Name | sepS |
| Function | O-phosphoserine--tRNA ligase |
| Gene Symbol | sepS |
| Trusted Cutoff | 380.65 |
| Domain Trusted Cutoff | 380.65 |
| Noise Cutoff | 307.85 |
| Domain Noise Cutoff | 307.85 |
| Isology Type | equivalog |
| EC Number | 6.1.1.27 |
| HMM Length | 533 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Serine family |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:09PM |
| Last Modified | Jan 9 2012 11:49AM |
| Comment | This family of archaeal proteins resembles known phenylalanyl-tRNA synthetase alpha chains. Recently, it was shown to act in a proposed pathway of tRNA(Cys) indirect aminoacylation, resulting in Cys biosynthesis from O-phosphoserine, in certain archaea. It charges tRNA(Cys) with O-phosphoserine. The pscS gene product converts the phosphoserine to Cys. |
| References | SE TIGR
AL clustalw
RN [1]
RM 15790858
RT RNA-dependent cysteine biosynthesis in archaea.
RA Sauerwald A, Zhu W, Major TA, Roy H, Palioura S, Jahn D, Whitman WB, Yates JR 3rd, Ibba M, Soll D.
RL Science. 2005 Mar 25;307(5717):1969-72. |
| Genome Property | GenProp0304: cysteine biosynthesis, tRNA-dependent (HMM) |
