HMM Summary Page: TIGR00505

FunctionGTP cyclohydrolase II
Gene SymbolribA
Trusted Cutoff205.85
Domain Trusted Cutoff205.85
Noise Cutoff98.50
Domain Noise Cutoff98.50
Isology Typeequivalog_domain
EC Number3.5.4.25
HMM Length191
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryRiboflavin, FMN, and FAD
Gene Ontology TermGO:0003935: GTP cyclohydrolase II activity molecular_function
GO:0009231: riboflavin biosynthetic process biological_process
AuthorAnolik RT, Richardson DL
Entry DateApr 20 1999 2:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentSeveral members of the family are bifunctional, involving both ribA and ribB function. In these cases, ribA tends to be on the C-terminal end of the protein and ribB tends to be on the N-terminal. The function of archaeal members of the family has not been demonstrated and is assigned tentatively.
ReferencesSE AL DR ECOCYC; ribA; DR EXPERIMENTAL; EGAD|9119|EC1277; Escherichia coli DR EXPERIMENTAL; EGAD|77371|83427; Pichia guilliermondii SE TIGR GA hmmls AL clustalw DR HAMAP; MF_01283; 46 of 46
Genome PropertyGenProp0112: riboflavin, FAD and FMN from GTP and ribulose-5-P (HMM)