| Accession | TIGR00512 |
| Name | salvage_mtnA |
| Function | S-methyl-5-thioribose-1-phosphate isomerase |
| Gene Symbol | mtnA |
| Trusted Cutoff | 279.00 |
| Domain Trusted Cutoff | 279.00 |
| Noise Cutoff | 234.35 |
| Domain Noise Cutoff | 234.35 |
| Isology Type | equivalog |
| EC Number | 5.3.1.23 |
| HMM Length | 335 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Aspartate family |
| Gene Ontology Term | GO:0019509: L-methionine salvage from methylthioadenosine biological_process |
| | GO:0046523: S-methyl-5-thioribose-1-phosphate isomerase activity molecular_function |
| Author | Haft DH |
| Entry Date | Oct 18 1999 5:03PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The delineation of this family was based in part on a discussion and neighbor-joining phylogenetic study, by Kyrpides and Woese, of archaeal and other proteins homologous to the alpha, beta, and delta subunits of eukaryotic initiation factor 2B (eIF-2B), a five-subunit molecule that catalyzes GTP recycling for eIF-2. This clade is now recognized to include the methionine salvage pathway enzyme MtnA. |
| References | RN [2]
RM 98188271
RT Archaeal translation initiation revisited: the initiation factor 2 and eukaryotic initiation factor 2B alpha-beta-delta subunit families.
RA Kyrpides NC, Woese CR
RL Proc Natl Acad Sci U S A 1998 Mar 31;95(7):3726-30
DR HAMAP; MF_01678; 159 of 164 |
| Genome Property | GenProp0729: methionine salvage from methylthioadenosine (HMM) |