Accession | TIGR00522 |
Name | dph5 |
Function | diphthine synthase |
Gene Symbol | dph5 |
Trusted Cutoff | 114.30 |
Domain Trusted Cutoff | 114.30 |
Noise Cutoff | 113.75 |
Domain Noise Cutoff | 113.75 |
Isology Type | equivalog |
EC Number | 2.1.1.98 |
HMM Length | 258 |
Mainrole Category | Protein fate |
Subrole Category | Protein modification and repair |
Gene Ontology Term | GO:0004164: diphthine synthase activity molecular_function |
| GO:0017183: peptidyl-diphthamide biosynthetic process from peptidyl-histidine biological_process |
Author | Haft DH |
Entry Date | Oct 18 1999 5:03PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Alternate name: diphthamide biosynthesis S-adenosylmethionine-dependent methyltransferase.
This protein participates in the modification of a specific His of elongation factor 2 of eukarotes and Archaea to diphthamide. The protein was characterized in Saccharomyces cerevisiae and designated DPH5. |
References | RM 92375071
RT DPH5, a methyltransferase gene required for diphthamide biosynthesis in Saccharomyces cerevisiae.
RA Mattheakis LC, Shen WH, Collier RJ
RL Mol Cell Biol 1992 Sep;12(9):4026-37
DR HAMAP; MF_01084; 32 of 38 |
Genome Property | GenProp0831: archaeal core gene set, exactly 1 per genome (HMM) |