Accession | TIGR00535 |
Name | SAM_DCase |
Function | S-adenosylmethionine decarboxylase proenzyme |
Trusted Cutoff | 233.15 |
Domain Trusted Cutoff | 233.15 |
Noise Cutoff | 127.30 |
Domain Noise Cutoff | 127.30 |
Isology Type | equivalog |
EC Number | 4.1.1.50 |
HMM Length | 334 |
Mainrole Category | Central intermediary metabolism |
Subrole Category | Polyamine biosynthesis |
Gene Ontology Term | GO:0004014: adenosylmethionine decarboxylase activity molecular_function |
| GO:0006597: spermine biosynthetic process biological_process |
| GO:0008295: spermidine biosynthetic process biological_process |
Author | Haft DH |
Entry Date | Oct 19 1999 4:29PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This enzyme is a key regulatory enzyme of the polyamine synthetic pathway.
This protein is a pyruvoyl-dependent enzyme. The proenzyme is cleaved at a Ser residue that becomes a pyruvoyl group active site. |
References | A2 hmmalign
AL ClustalW
DR PROSITE; PDOC01038; S-adenosylmethionine decarboxylase signature; |