Accession | TIGR00542 |
Name | hxl6Piso_put |
Function | putative hexulose-6-phosphate isomerase |
Trusted Cutoff | 272.15 |
Domain Trusted Cutoff | 272.15 |
Noise Cutoff | 188.50 |
Domain Noise Cutoff | 188.50 |
Isology Type | hypoth_equivalog |
HMM Length | 279 |
Mainrole Category | Energy metabolism |
Subrole Category | Sugars |
Author | Haft DH |
Entry Date | Oct 19 1999 4:29PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This family shows similarity by PSI-BLAST to other isomerases. Putative identification as hexulose-6-phosphate isomerase is reported in Swiss-Prot, attributing a discussion in Genome Sci. Technol. 1:53-75(1996).
This family is conserved at better than 40 % identity among the four known examples from three species: Escherichia coli (SgbU and SgaU), Haemophilus influenzae, and Mycoplasma pneumoniae. The rarity of the family, high level of conservation, and proposed catabolic role suggests lateral transfer may be a part of the evolutionary history of this protein. |
References | GA hmmsearch
DR SWISSPROT; P37679;
DR SWISSPROT; P39305;
DR ECOCYC; EG12286; SGBU
RN [1]
RA REIZER J., CHARBIT A., REIZER A., SAIER M.H. JR.;
RT "Novel phosphotransferases system genes revealed by bacterial genome analysis: operons encoding homologues of sugar-specific permease domains of the phosphotransferase system and pentose catabolic enzymes."
RL GENOME SCI. TECHNOL. 1:53-75(1996).
DR HAMAP; MF_01951; 18 of 19 |