| Accession | TIGR00557 |
| Name | pdxA |
| Function | 4-hydroxythreonine-4-phosphate dehydrogenase PdxA |
| Gene Symbol | pdxA |
| Trusted Cutoff | 290.35 |
| Domain Trusted Cutoff | 290.35 |
| Noise Cutoff | 252.75 |
| Domain Noise Cutoff | 252.75 |
| Isology Type | equivalog |
| EC Number | 1.1.1.262 |
| HMM Length | 320 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Pyridoxine |
| Gene Ontology Term | GO:0008615: pyridoxine biosynthetic process biological_process |
| | GO:0050570: 4-hydroxythreonine-4-phosphate dehydrogenase activity molecular_function |
| Author | Haft DH |
| Entry Date | Oct 19 1999 4:30PM |
| Last Modified | May 16 2012 6:50PM |
| Comment | This HMM represents PdxA, an NAD+-dependent 4-hydroxythreonine 4-phosphate dehydrogenase (EC 1.1.1.262) active in pyridoxal phosphate biosynthesis. |
| References | RM 99239931
RT Vitamin B6 biosynthesis: formation of pyridoxine 5'-phosphate from 4-(phosphohydroxy)-L-threonine and 1-deoxy-D-xylulose-5-phosphate by PdxA and PdxJ protein.
RA Laber B, Maurer W, Scharf S, Stepusin K, Schmidt FS
RL FEBS Lett 1999 Apr 16;449(1):45-8
DR HAMAP; MF_00536; 96 of 101 |
| Genome Property | GenProp0862: pyridoxal phosphate biosynthesis, PdxA/PdxJ pathway (HMM) |
